Postdoctoral researcher · Temple University

John B. Allard

Machine learning, comparative genomics, and phylogenetics

I develop machine-learning methods to uncover the genetic basis of shared traits across species, with a focus on longevity and aging.

John B. Allard

Research

I study the genetic basis of traits that have evolved independently in different species, using comparative genomics and machine learning.

01

Machine learning for
comparative genomics

Developing interpretable models that identify genes and sequence changes associated with traits that evolved independently across species.

Evolutionary sparse learning
02

The genetics of
longevity & aging

Investigating what independently evolved long lifespans can tell us about the genes and biological pathways underlying longevity.

03

Phylogenetics &
scientific software

I study species’ evolutionary histories and build tools for viewing large phylogenies and extracting trees from published images.

Explore the tools

Work in progress

A timed molecular phylogeny of 485,000 species reveals a pan-eukaryotic link between evolutionary rate and species diversity

The tree contains 484,771 tips. The view starts at Homo sapiens and zooms out to the full eukaryotic phylogeny, with taxonomy ribbons showing broader groups as the scale changes. Rendered in Big Tree Viewer.

Software

I develop software for viewing and digitizing phylogenetic trees and analyzing comparative genomic data.

A phylogenetic tree in Big Tree Viewer’s spiral layout, with colored taxonomy ribbons following its coils.

Browser application

Big Tree Viewer

Explore very large phylogenetic trees directly in your browser. Navigate evolutionary relationships, add taxonomic context, and export figures.

Treemble desktop interface with nodes marked on a published phylogenetic tree image.

Desktop application · macOS & Windows

Treemble

Turn published phylogeny images into machine-readable Newick trees. Recover evolutionary data for new analyses, comparisons, and synthesis.

Figure 1 from the ESL-PSC Toolkit manuscript: analysis settings, phylogenetic pair selection, phenotype thresholds, and sequence-site results.

Comparative genomics toolkit

ESL-PSC Toolkit

A graphical environment for designing phylogenetic contrasts, fitting models of convergent traits, and examining genes and sequence sites.

Figure 1, Allard & Kumar, Molecular Biology and Evolution (2026).

Selected publications

Full list on Google Scholar
2026

Nature Reviews Genetics

The genetic foundations of convergent traits

John B. Allard and Sudhir Kumar

About this work

A review of the genetic mechanisms behind repeated trait evolution and the computational approaches used to distinguish adaptive convergence from background similarity.

Review
2025

Nature Communications

Evolutionary sparse learning reveals the shared genetic basis of convergent traits

John B. Allard, Sudip Sharma, Ravi Patel, Maxwell Sanderford, Koichiro Tamura, Slobodan Vucetic, Glenn S. Gerhard, and Sudhir Kumar

About this work

Phylogeny-informed machine learning identifies genetic signals associated with independently evolved traits, demonstrated with echolocation in mammals and C4 photosynthesis in grasses.

Research

About me

Postdoctoral researcher
Philadelphia, Pennsylvania

I’m a postdoctoral researcher in Sudhir Kumar’s lab at Temple University, in the Institute for Genomics and Evolutionary Medicine and the Department of Biology.

My work focuses on machine-learning methods for comparative genomics, particularly the genetic basis of longevity and aging. I also work on phylogenetics, both to account for shared ancestry in comparative analyses and to make published phylogenetic data easier to use.

Before my doctoral work, I studied insulin-like growth factor signaling and longevity regulation in short-lived killifish at the University of Michigan. My Ph.D. research at Temple focused on machine learning and comparative genomics to identify shared genetic signatures of convergent traits.

Education

Ph.D. in Bioinformatics 2026
Temple University · Advisor: Sudhir Kumar
M.S. in Molecular, Cellular, and Developmental Biology
University of Michigan
B.S. in Cellular and Molecular Biology
University of Michigan

Contact

You can reach me by email about my research or software.

john.allard@temple.edu